kras g12d — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78212	RMC-9805	KRAS G12D inhibitor 18,KRAS G12D IN 18	Others
	RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.		Others
T40282	KRAS G12D inhibitor 7
	KRAS G12D inhibitor 7, is a highly potent inhibitor specifically targeting KRAS G12D.
T9674	KRAS G12D inhibitor 1
	KRAS G12D inhibitor 1 (example 243) is an inhibitor of KRAS G12D with an IC 50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation [1].
T40281	KRAS G12D inhibitor 6
	KRAS G12D inhibitor 6 is an efficacious compound that effectively inhibits KRAS G12D.
T40246	KRAS G12D inhibitor 5
	KRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential treatment of pancreatic cancer.
T77804	KRAS G12D mutation regulator 4
	KRAS G12D mutation regulator 4 can be used in studies about Ras.
T9303	MRTX1133		Ras
	MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.		Ras
T11224	Rineterkib	ERK-IN-1	ERK , Raf
	Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.		ERK , Raf
T64178	KRAS G12D inhibitor 13
	KRAS G12D inhibitor 13 is a potent inhibitor of KRAS G12D. KRAS G12D inhibitor 13 has shown potential for the investigation of KRAS G12D-mediated cancers.
T62228	KRAS G12D inhibitor 14		Ras
	KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM). KRAS G12D inhibitor 14 inhibits the active form of KRAS G12D (KRAS G12D-GTP), but not KRAS G13D.		Ras
T63577	KRAS G12D inhibitor 11
	KRAS G12D inhibitor 11 is a potent inhibitor of KRAS G12D. The Ras family of proteins are important intracellular signaling molecules that play an important role in growth and development, and KRAS G12D inhibitor 11 has ...
T72394	KRAS G12D inhibitor 3
	KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less than 500 nM.
T74663	KRAS G12D inhibitor 17
	KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.
T63028	KRAS G12D inhibitor 12
	KRAS G12D inhibitor 12 is an effective inhibitor of KRAS G12D. The Ras protein family is an important intracellular signaling molecule, which plays an important role in growth and development. KRAS G12D inhibitor 12 has ...
T64031	KRAS G12D inhibitor 9
	KRAS G12D inhibitor 9 is a potent inhibitor of KRAS G12D. Among them, the RAS protein family is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 9 ...
T72345	KRAS G12D inhibitor 10
	KRAS G12D Inhibitor 10 is a potent agent targeting the KRAS G12D mutation, a variant in the Ras protein family crucial for cellular growth and development. This compound shows promise for investigating cancers mediated b...
T79072	KRAS G12D modulator-1		Ras
	KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].		Ras
T74607	KRAS G12D inhibitor 15
	KRAS G12D inhibitor 15 is a potent inhibitor specifically targeting the KRAS G12D mutation. It holds potential for research into numerous diseases or disorders, including cancer and its metastases[1].
T72355	KRAS G12D inhibitor 16
	KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant t...
T73828	KRAS G12D inhibitor 3 TFA
	KRAS G12D Inhibitor 3 TFA, exhibiting an inhibitory concentration (IC50) of less than 500 nM, is effective as an antitumor agent.